Rheumatoid Arthritis
ARFANIL



Modern medicine has not yet found a cure for arthritis, and through the process of trying to find one, it has created an entirely new set of problems. Each year, an estimated 100,000 people are hospitalized and 16,000 patients die from side effects caused by commonly prescribed arthritis medications. (USA 2002) The need for safer treatment methods has inspired an ongoing flurry of research and drug development by pharmaceutical companies. NSAID’s while helpful to some degree in alleviating the pain of arthritis, certainly have their share of side effects. Even the latest “super aspirins”, which are designed to target only the COX-2 enzymes, may have their drawbacks. In fact by blocking one type of ecosionide, it creates imbalance, which leads to side effects. (Ref: The Arthritis Miracle. Earle Mindell, Penguin Putnam, New York, 2003)

Herbs have huge untapped potential as a natural remedy for inflammatory conditions. The herbal extract’s many active components have a balancing, equalizing effect on the body, bringing pro and anti-inflammatory hormones into proper balance. The antioxidants that occur naturally in the herbs help break the cycle of free radical formation that can be so damaging in chronic inflammation. And what makes herbal extract so much more attractive than NSAID’s is that they can relieve the pain and inflammation of arthritic joints without the common side effects that accompany drugs.

Rheumatoid arthritis: This is a disease of modern civilization. It is a severe and painful condition with chronic inflammation of the tough fibrous material or connective tissues that hold the parts of body together. Many patients run a course of slowly progressive joint destruction and deformities. Rheumatoid Factor (RF) is an immunoglobin (lgM) of high molecular weight detectable in the blood in this type of patients.

The herbo mineral formula contains standardised Herbal Extracts. The formulation is tested for toxicity, (LD50 is 117 gms/day). Double blind Cross over Clinical studies have indicated decrease in Severity of pain (score), Morning stiffness (minutes), Joint score, Ritche articular index, Disability score & Erythrocyte sedimentation rate (mm/hr), while improving Grip strength (mm Hg). The most important observation is Seroconversion, an important landmark in this drug development process of Arfanil.

The formulation is patented in South Africa SA (SA95/00908 DEC 1995) & in India (183037 Dec 1999)

Table of Contents

Introduction
Ingredients & Pharmacology of Ingredients
Indications & Patent Details
Dosage and Supporting Formulations
Safety of the Formulation
Abstract from Clinical Trial Report
Raw Material Testing & Standardization
Finished Product Testing & A Typical Lab Report